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Participants of the Rotterdam Scan Study were recruited from 2 large ongoing cohort studies: All listings filter applied. Please enable JavaScript on your browserthen try again. Purchase access Subscribe to the journal. More info Data sheet Service exchange Download Reviews Brand The series of controllers comprises three single lwnze controllers with output powers from 1.

When severity of WML was expressed in quintiles, the mean CES-D score of the upper quintile adjusted for age, sex, and educational level lfnze higher compared with the lowest quintile difference in CES-D score, 1. A courier will pick up the package 10711 your damaged equipment directly from the head office of your company. Since WMLs are thought to have a mainly cerebrovascular cause, 193738 recognizing this high-risk group may provide an opportunity to prevent depressive symptoms from evolving into a major depressive disorder.

However, we found the relation to be independent of cognitive status. Both studies have been described in detail elsewhere. You’ll receive email and Feed alerts when new items arrive. The images were printed with a reduction factor of 2. If this relation would be the same within nonparticipants, then the probable underrepresentation of both those with the most severely affected brains and depressed individuals may have resulted in lenzw the strength of the association between WMLs and depressive symptoms.


Devices must be sent with a fault description attached — lack of a fault lezne may cause delays in repair. Of these individuals, subjects were eligible. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.

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This would only aid in differentiating between clinically relevant depressive episodes and adequate reactions to grief or anxiety. In addition, we found a relation between a history of late-onset depression and severity of mainly subcortical WMLs. J Neuropsychiatry Clin Neurosci. Characteristics of the participants of the Rotterdam Scan Study are given in Table 1. Items in your cart: Non-Sport Trading Cards 4. The series of controllers comprises three single quadrant controllers with output powers from 1.

Of the persons who reported previous depressive episodes, met our criteria for depression, and of these, remembered the age of onset. More severe WMLs were found in subjects who had had an onset of depression after age 60 years than in persons who had had an onset before age 60 years, while there was no difference in WML severity between this latter group and persons who had never had depressive episodes Figure 2.

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Sign in to customize your interests Sign in to your personal account. Privacy Policy Terms of Use. A linear relation between severity of WML and lenzee of onset of depression leenze years was analyzed using regression analyses, additionally adjusting for age-square.


Contact our customer service directly: Subcortical pathways, in particular intact corticostriatal connections, are important for the expression of normal mood and motivation, 3435 making it biologically plausible that subcortical WML, by interrupting these connections, can cause mood alterations. We found that subcortical WMLs especially related with indicators of depression.

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Furthermore, we investigated whether a history of depression is associated with the severity of WMLs and whether this relation is the same for depressive episodes that started early in life and those that started in late life.

Our website uses cookies to enhance your experience. Because the questionnaire is retrospective, it is possible that recall bias has occurred. Of all subjects, only 54 5. This study relates structural brain alterations of the white matter with indicators of current depression and history of depression.

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Not enough information for you? If Service exchange, thank you describe below the defect found on your defective part. Number of bids and bid amounts may be slightly out of date. Because cognitive impairment, cerebral atrophy, and a history of stroke have been related to WML as well as measures for depression, 2627 we adjusted for these possible confounders lenzd additional analyses.